A study published in the BMJ highlights the effectiveness of viscosupplements like Cingal in managing knee osteoarthritis pain. By restoring the joint’s natural lubrication through hyaluronic acid, these treatments provide significant relief and improved mobility for patients.

While Cingal is generally well-tolerated and considered safe, understanding its potential side effects is essential for informed decision-making. Common reactions are mild and short-lived, but consulting with a healthcare provider ensures the treatment is tailored to individual needs and minimizes risks.

This article outlines the complete list of Cingal side effects, helping you weigh the benefits and considerations of this advanced treatment for knee osteoarthritis.

Key Takeaways

  • Cingal injections can cause common side effects such as temporary swelling, redness, and tenderness at the injection site.
  • Less common side effects include allergic reactions, joint stiffness, and the risk of infection.
  • It is crucial to select the right patients, adhere to proper injection techniques, and follow post-treatment care instructions to minimize these risks and ensure patient safety.
  • Medical professionals play a vital role in monitoring and managing side effects, and patients should seek medical attention for severe side effects.

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Common Side Effects of Cingal Injections

Cingal injections are a trusted treatment for knee osteoarthritis, providing long-lasting pain relief and improved joint function. However, like any medical procedure, they may cause temporary side effects. Common side effects include:

close up knee injection
  • Swelling: Temporary fluid buildup at the injection site, often resolving within a few days.
  • Pain: Mild discomfort or soreness post-injection, typically subsiding quickly.
  • Redness: A slight flushed appearance or irritation around the treated area, common immediately after the procedure.
  • Tenderness: Sensitivity or discomfort when touched, a normal response as the body adjusts to the treatment.

Less Common Side Effects of Cingal Injections

While Cingal injections are generally safe, less common side effects may occur in some patients. These include:

  • Allergic Reactions: Rare but serious allergic reactions may include itching, swelling of the face or lips, or difficulty breathing. Patients experiencing any of these symptoms should seek immediate medical attention.
  • Joint Stiffness: Some patients report temporary stiffness after the injection, which may hinder activities like walking or climbing stairs. While this usually resolves within days, persistent stiffness should be evaluated by a healthcare provider.
  • Infection Risk: Though uncommon, infections at the injection site are a potential risk. Symptoms such as increasing pain, warmth, swelling, or fever warrant immediate medical consultation to prevent complications.

The widespread use and approval of Cingal in various countries underscore its general safety for most patients. Awareness of these less common reactions allows for timely intervention, enhancing overall treatment safety and effectiveness.

Minimizing Risks and Ensuring Patient Safety

Identifying suitable candidates for Cingal injections is the first step in ensuring safety. Cingal is particularly effective for patients with knee osteoarthritis who have not responded adequately to conservative treatments such as physical therapy or oral medications. A thorough medical history review and physical examination are important to rule out any contraindications, such as infections or allergies to the injection’s components.

knee ultrasound

Proper injection techniques are also essential to minimize risks and maximize the benefits of Cingal injections. The injection should be administered by a trained healthcare professional using aseptic techniques to prevent infection. Ultrasound guidance can ensure the injection’s accurate placement into the joint space. It is also important to avoid injecting into inflamed or infected joints, as this can increase the risk of adverse reactions.

Furthermore, post-treatment care instructions are crucial in minimizing risks and ensuring patient safety. Patients should be advised to rest the injected joint for 24-48 hours and avoid strenuous activities to allow the treatment to settle. Applying ice to the injection site can help reduce mild pain or swelling.

Patients should also be educated on the signs of potential complications, such as increased pain, redness, or fever, and instructed to contact their healthcare provider if these occur.

Managing Cingal Side Effects

Medical professionals are essential in identifying and managing side effects. Regular follow-up appointments allow for monitoring of patient responses to the injection and early detection of adverse reactions. 

talking to a doctor

Healthcare providers should educate patients about common side effects, such as localized pain, swelling, or redness at the injection site, and how to manage these symptoms at home. It is also vital to compare Cingal vs Synvisc in terms of safety profiles, as each treatment may present different side effects and benefits.

Patients should seek immediate medical attention if they experience severe side effects such as intense pain, significant swelling, fever, or signs of infection. Prompt intervention can prevent further complications and ensure patient safety.

Long-term Effects and Complications

Long-term effects and complications of Cingal injections are rare but should be communicated to patients. These may include persistent joint pain, allergic reactions, or worsening of symptoms. Patients should be aware of these potential risks and communicate openly with their healthcare provider to address any concerns.

Conclusion

Cingal injections offer a promising solution for managing knee osteoarthritis by combining hyaluronic acid and corticosteroids. This dual-action approach provides rapid relief from inflammation while enhancing joint lubrication, improving mobility and quality of life for patients. While generally safe and effective, understanding potential side effects and how to manage them is crucial for ensuring a positive treatment experience.

Awareness and proper management of side effects empower patients to make informed decisions about their knee osteoarthritis treatment journey.

FAQs

1. What is Cingal?

Cingal is an injectable treatment that combines hyaluronic acid and a corticosteroid to provide both immediate and long-term pain relief for patients with knee osteoarthritis. It’s designed to improve joint lubrication and reduce inflammation.

2. How long do the effects of Cingal last?

Cingal injections typically relieve pain and improve knee function for up to 26 weeks, with benefits often seen gradually over time.

3. Are there any serious risks with Cingal injections?

While rare, serious side effects can include allergic reactions (itching, difficulty breathing) or infection at the injection site (fever, redness, warmth). If any of these symptoms occur, patients should seek immediate medical attention.

4. What should I do after receiving a Cingal injection?

After the injection, rest the knee, apply ice to reduce swelling, and follow your doctor’s aftercare instructions. Contact your healthcare provider if you notice unusual symptoms or worsening side effects.

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References

Pereira TV, Jüni P, Saadat P, et al. Viscosupplementation for knee osteoarthritis: systematic review and meta-analysis. BMJ. Published online July 6, 2022:e069722. doi:https://doi.org/10.1136/bmj-2022-069722 

FAQs | Cingal. NEXT GENERATION, NON-OPIOID OA PAIN MANAGEMENT. Published June 10, 2016. https://www.cingal.com/the-patient-experience/faqs/