Viscosupplementation, a treatment involving the injection of hyaluronic acid into the knee joint, has been shown to improve joint function and reduce pain in osteoarthritis patients. This method works by supplementing the natural lubrication in the joint, facilitating smoother movement and providing pain relief.

One such treatment is Monovisc, a single-dose hyaluronic acid injection designed to provide long-lasting relief from knee osteoarthritis pain. While Monovisc is generally well-tolerated, like any treatment, it may cause certain side effects.

In this article, we will explore the potential Monovisc side effects, what to expect after treatment, and how to manage any possible complications.

Key Takeaways

  • Monovisc is a viscosupplement injection used to treat knee pain associated with osteoarthritis.
  • Common side effects of Monovisc include mild pain, swelling, stiffness, and discomfort at the injection site.
  • Rare side effects may include allergic reactions and infection at the injection site.
  • Serious side effects of Monovisc include severe joint pain, swelling, and signs of infection such as fever or chills.
  • It is essential to manage side effects by following the healthcare provider’s instructions and seeking medical advice if necessary.
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MONOVISC®

$349.00
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SYNVISC®

$329.00

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What is Monovisc?

Monovisc is a hyaluronic acid-based injection designed to treat knee osteoarthritis. It works as a substitute for the natural synovial fluid in the knee, helping to lubricate the joint and improve its smooth movement. Monovisc is a single-dose treatment, which sets it apart from other viscosupplementation therapies that require multiple injections.

The primary purpose of Monovisc is to relieve knee pain and improve joint mobility in patients with osteoarthritis. By mimicking the natural fluid in the knee, Monovisc helps to reduce friction between joint surfaces, leading to less pain and greater ease of movement. Many patients report significant pain relief and improved joint function following treatment.

Common Side Effects of Monovisc

Knee pain.

After a Monovisc injection, some patients may experience common side effects such as mild joint pain, stiffness, or swelling. These reactions are typically temporary and not serious, resolving within a few days as the body adjusts to the new joint fluid.

  • Mild Pain and Swelling at the Injection Site: These symptoms occur as the body reacts to the introduction of new hyaluronic acid into the joint. In most cases, the discomfort subsides within a few days without further complications.
  • Temporary Stiffness or Discomfort in the Joint: This reaction is normal and typically short-lived, often disappearing as the injection begins to take effect. Despite this stiffness, most patients can continue with their daily activities without significant issues.

Rare Side Effects of Monovisc

Itching.

While Monovisc is generally well-tolerated, rare side effects can occur. These reactions are uncommon but may include allergic responses or infections at the injection site.

  • Allergic Reactions such as Hives or Itching: Allergic reactions can manifest as a skin rash, facial or hand swelling, and chest tightness. These signs can occur right after the shot or a few hours later. If you notice these symptoms, seeking immediate medical attention is essential, especially if you experience difficulty breathing or chest tightness.
  • Infection at the Injection Site: While uncommon, infections can be serious and may present as warmth, redness, swelling, or pus near the area where the injection was given. If these symptoms occur, prompt treatment is essential to prevent further complications.

Serious Side Effects of Monovisc

High temperature.

While serious side effects of Monovisc are rare, they can occur. These include severe joint pain, swelling, and signs of infection such as fever or chills. If any of these symptoms arise, it is crucial to seek immediate medical attention to prevent complications.

  • Severe Joint Pain or Swelling: In rare cases, some patients may experience severe joint pain or swelling after a Monovisc injection. This could indicate an adverse reaction to the treatment or another underlying issue. If this occurs, contacting your doctor promptly is essential, as it may require immediate medical intervention.
  • Signs of Infection such as Fever or Chills: If symptoms such as fever, chills, or increased warmth and redness around the injection site develop, it could be a sign of infection. Infections are a serious concern and must be treated as soon as possible to prevent further complications. If these signs appear, immediate medical attention is critical.

Managing Monovisc Side Effects

Most Monovisc side effects, such as mild pain, swelling, or temporary stiffness, are manageable and often resolve on their own within a few days. To alleviate these symptoms, consider the following tips:

  • Apply a cold pack to the injection site to reduce swelling and discomfort.
  • Avoid strenuous activities for 24 to 48 hours after the injection to allow the knee to rest.
  • Take over-the-counter pain relievers, such as acetaminophen, as recommended by your healthcare provider.
  • Elevate the leg and avoid putting too much weight on the knee to promote faster recovery.

If common side effects persist or worsen, it’s important to contact a healthcare provider. Signs to watch for include prolonged pain, excessive swelling, or any other unexpected symptoms that do not subside after a few days. Additionally, seek medical advice immediately if you experience any signs of an allergic reaction, such as itching, hives, or facial swelling.

Steps to Take in Case of Serious Side Effects

While serious Monovisc side effects are rare, patients must know what to do and how to respond if they occur. These may include severe joint pain, signs of infection, or allergic reactions. If you experience any of the following, take immediate action:

  • Contact your healthcare provider if you notice severe joint pain, fever, chills, or warmth at the injection site.
  • Seek emergency medical care if symptoms like chest tightness, difficulty breathing, or severe swelling in the face or throat occur.
  • Keep track of your Monovisc dosage and inform your doctor if you’ve had previous adverse reactions to similar treatments.

Conclusion

Monovisc, like any medical treatment, can cause side effects ranging from mild to severe. While some people may experience minor discomfort such as pain or swelling at the injection site, others could develop more serious complications, such as severe joint pain or signs of infection, including fever.

If you experience any serious reactions after receiving Monovisc, it’s important to contact your doctor immediately. Early intervention can help manage side effects and ensure your safety. Being aware of these potential side effects allows you to make an informed decision about using Monovisc for knee pain relief.

FAQs

1. What are Monovisc side effects?

Monovisc side effects can include a variety of symptoms, such as joint pain or swelling, itching at the injection site, and sometimes more severe reactions.

2. Are all Monovisc side effects common?

No, not all side effects are common. Some people might experience minor discomfort, while others could have more severe reactions. It’s essential to consult with your doctor for a complete list of possible outcomes.

3. Can I prevent these side effects?

While avoiding side effects altogether is impossible, certain precautions like following your doctor’s instructions closely can help reduce their likelihood.

4. What should I do if I experience these side effects?

If you encounter any adverse reaction after receiving Monovisc treatment, contact your healthcare provider immediately for advice and guidance.

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References

Foran, JRH. Viscosupplementation for knee arthritis. American Academy of Orthopaedic Surgeons. https://orthoinfo.aaos.org/en/treatment/viscosupplementation-treatment-for-knee-arthritis/

Anika Therapeutics. (n.d.). Monovisc: For healthcare professionals. Retrieved October 8, 2024, from https://monovisc.ca/en/professionals