A 2019 study on viscosupplementation for knee osteoarthritis (OA) found that this treatment significantly reduces pain, enhances muscle strength, and improves joint function in patients suffering from this degenerative condition. These findings support the long-term effectiveness of viscosupplementation in managing osteoarthritis symptoms and improving mobility.

Monovisc and Orthovisc are two popular hyaluronic acid injections. Monovisc is a single-dose injection, while Orthovisc requires a series of three or four injections. Both treatments aim to relieve knee osteoarthritis by improving joint lubrication and reducing inflammation.

In this article, we will explore the effectiveness of Monovisc injections for knees, compare them with Orthovisc, and provide insights into their benefits and potential drawbacks.

Key Takeaways

  • Monovisc is a single-injection treatment for osteoarthritis that provides pain relief for up to six months.
  • Orthovisc requires a series of three to four injections, also offering relief lasting up to six months.
  • Both injections use hyaluronic acid to improve joint lubrication and reduce pain.
  • Monovisc offers the convenience of fewer doctor visits, while Orthovisc spreads the treatment over several weeks.
  • The choice between Monovisc and Orthovisc depends on patient preference for fewer injections or a more gradual treatment approach.
Monovisc Eng Front

MONOVISC®

$349.00
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SYNVISC®

$329.00

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Understanding Osteoarthritis and Treatment Options

Knee injection.

Osteoarthritis is a degenerative joint disease that occurs when the protective cartilage cushioning the joints wears down over time. This leads to pain, swelling, and stiffness, particularly in weight-bearing joints like the knees. As the cartilage deteriorates, bones can rub against each other, causing discomfort and limiting mobility.

Managing osteoarthritis effectively is crucial for maintaining joint function and reducing pain. Without proper treatment, the condition can severely impact daily activities, making even simple movements difficult. Effective treatment options, such as hyaluronic acid injections like Monovisc and Orthovisc, can help alleviate pain, improve mobility, and potentially delay the need for surgical intervention.

Monovisc

Knee injection.

Monovisc is a hyaluronic acid-based injection designed to alleviate knee pain caused by osteoarthritis. Hyaluronic acid is a natural substance found in joint fluid that acts as a lubricant and shock absorber. In osteoarthritis patients, the levels of this essential compound decrease, leading to joint pain and stiffness. Monovisc works by replenishing this lost lubrication, which helps to restore smoother joint movement and reduce discomfort.

What sets Monovisc apart from other treatments like Orthovisc is its convenient single-injection protocol. Unlike treatments that require multiple doses over a period of weeks, Monovisc delivers its high concentration of hyaluronic acid in just one injection. This makes the treatment process quicker and easier for patients, reducing the number of doctor visits required.

Studies have demonstrated the effectiveness of Monovisc in treating osteoarthritis, with many patients experiencing significant reductions in pain and improved joint mobility after treatment. Despite the potential Monovisc side effects, many find relief with this injection.

Orthovisc

Knee injection.

Orthovisc is another hyaluronic acid-based injection used to treat knee osteoarthritis, designed to improve joint lubrication and reduce pain. Like Monovisc, Orthovisc contains hyaluronic acid, a naturally occurring substance that helps cushion and lubricate joints. In osteoarthritis patients, the reduced levels of hyaluronic acid contribute to joint discomfort and stiffness, and Orthovisc works to replenish this essential component, allowing smoother movement and alleviating pain.

The administration protocol for Orthovisc differs from Monovisc, as it requires a series of three or four injections given over the course of several weeks. Each injection is spaced one week apart, allowing the hyaluronic acid to gradually accumulate in the joint and provide ongoing relief. While this multi-dose approach requires more frequent visits to the doctor, it offers a steady improvement in joint lubrication and pain reduction over time.

Orthovisc has been shown to be effective in treating osteoarthritis, particularly for patients who have not responded to other treatments like physical therapy or oral medications. Many patients report significant reductions in pain and improved mobility following the full course of injections.

Comparing Monovisc and Orthovisc

Monovisc and Orthovisc are both effective in providing pain relief for knee osteoarthritis, with results lasting up to six months. Monovisc achieves this relief with a single injection, offering convenience and fewer doctor visits. In contrast, Orthovisc requires a series of three to four injections spaced over several weeks to achieve the same duration of relief.

Patient Satisfaction and Testimonials

On Monovisc:

  • “I had my first Monovisc injection in September 2019; my second was due in March 2020, but then COVID hit. Finally, I was able to have the second injection in May 2020. These injections have been great for both knees. I am bone on bone in my right knee. I went to two different Orthopedic Surgeons before having the injections. Both recommended getting them, and I am so happy I did. No pain, no issues with the injections, and they help! I will continue with the Monovisc injections until I can’t have them or they don’t work. Both surgeons said I can continue these until they don’t work; some patients continue and never need knee replacement. Wouldn’t that be great? It’s a big yes vote from me.”

On Orthovisc:

  • “I am going in for my second shot of Orthovisc for both knees. I was extremely skeptical about it but gave it a try since the cortisone treatments only lasted a few months. My first round of shots of Orthovisc was fantastic! I felt relief in a short space of time. No more concrete-like heaviness in the knees or crackling and shooting pain, except in the winter. Mine were in a lot of pain due to fibromyalgia and osteoarthritis, plus a car accident where they got smushed between two cars. So there was A LOT to the pain. Orthovisc worked wonders for me. Plus, it has been helpful for 1-2 years. I can’t remember how long it’s been, but it’s been quite a while, maybe three years. I hope the second round works as well as the first did. And that everyone using it will find similar relief in it.”

Conclusion

When deciding between Monovisc and Orthovisc, both offer effective relief for knee osteoarthritis, lasting up to six months. Monovisc requires just one injection, making it more convenient for those seeking fewer doctor visits, while Orthovisc involves a series of three to four injections.

The choice ultimately depends on your preference for treatment ease and your willingness to accommodate more frequent appointments. Consider your schedule and discuss with your healthcare provider to determine the best option for your needs.

FAQs

1. What are Monovisc and Orthovisc?

Both Monovisc and Orthovisc are used to treat knee osteoarthritis by improving joint lubrication and reducing pain.

2. How long do Monovisc and Orthovisc treatments last?

Both treatments can provide pain relief for up to six months.

3. How many injections are required for Monovisc and Orthovisc?

Monovisc requires only one injection, while Orthovisc requires three to four injections over several weeks.

4. Which treatment is better for osteoarthritis?

Effectiveness varies between individuals. Monovisc offers the convenience of fewer injections, while Orthovisc spreads the treatment over multiple sessions. Consult your doctor to determine which is best for your condition.

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References

Maia, P. A. V., Cossich, V. R. A., Salles-Neto, J. I., Aguiar, D. P., & de Sousa, E. B. (2019). Viscosupplementation improves pain, function and muscle strength, but not proprioception, in patients with knee osteoarthritis: a prospective randomized trial. Clinics (Sao Paulo, Brazil), 74, e1207. https://doi.org/10.6061/clinics/2019/e1207 

Anika Therapeutics. (n.d.). Monovisc: For healthcare professionals. Retrieved October 8, 2024, from https://monovisc.ca/en/professionals