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Orthopedic Injections
Orthopaedic injections contain therapeutic substances such as corticosteroids, hyaluronic acid, or platelet-rich plasma. They are administered intra-articularly into joints affected by conditions like arthritis and are used in combination with conservative management strategies.
Before you purchase orthopaedic injections, let’s review their therapeutic uses, types, administration techniques, and popular brands.
Orthopaedic injections are given directly into the joints, particularly the wrist, spine, shoulder, knee, hip, elbow, and ankle joints, and their surrounding ligaments/tendons.
They are often used as backup therapy to reduce pain and inflammation and improve function and mobility when more conservative measures fail.
Orthopaedic injections are used to:
How long orthopaedic injections last depends on their type.
For example, hyaluronic acid injections have been shown to last over 12 months in most cases.
The duration of action of corticosteroid injection is short-lived, often around two weeks. Some people report improvement in pain symptoms for up to 26 weeks.
Placental tissue matrix injections also produce symptomatic improvement in arthritis for over 12 months.
Finally, intra-articular injections of platelet-rich plasma provide pain relief for 4 to 12 months.
Here’s how to administer orthopaedic injections in general:
The side effects and complications of orthopaedic injections can be divided into minor and severe effects. The likelihood of minor side effects is greater, but they often resolve on their own. Severe side effects occur rarely but often become a medical emergency.
Minor side effects include:
Severe side effects include:
Orthopaedic injections have different types based on the active component. Here are four types to know about:
Hyaluronic acid (HA) application, also known as viscosupplementation, are a type of orthopaedic injectable used for the management of osteoarthritis pain.
Exogenously injected HA increases joint lubrication and cushioning. Increased viscosity of the joint fluid also improves shock absorption and joint mechanics.
High molecular weight HA has also been shown to produce an anti-inflammatory response, although this remains a debated effect.
Corticosteroid injections offer rapid and often dramatic pain relief. They downregulate the production of pro-inflammatory cytokines and enzymes to decrease joint inflammation and pain.
Placental tissue matrix (PTM) injections are a relatively novel type of orthopaedic injection. They provide a concentrated source of growth factors like IGF-1, TGF-β, and PDGF, which can stimulate chondrogenesis, tendon and ligament repair, and bone healing.
PTM injections also contain immunomodulatory factors that decrease inflammation and create a favorable environment for healing.
Platelet-rich plasma (PRP) injections are a regenerative therapy gaining traction in orthopedics. They use a patient’s own blood, which undergoes centrifugation to deliver a concentrated mixture of growth factors and cytokines such as PDGF, TGF-β, VEGF, and EDF directly to the injured site.
When injected, these growth factors lead to cell proliferation and migration of fibroblasts, chondrocytes, and tenocytes. They also cause collagen synthesis and angiogenesis.
SYNVISC®, ORTHOVISC®, and DUROLANE® are some popular orthopaedic treatment brands. Other brands include CRESPINE®, EUFLEXXA®, HYALGAN®, and MONOVISC®.
Formerly administered in three separate doses, SYNVISC® is now available as a single application under the name SYNVISC ONE®. It’s a gel-like solutuion derived from hyaluronan that is sourced from rooster combs.
Hyaluronan, which is naturally found in joints, functions as a lubricant and shock absorber, improving joint functionality.
SYNVISC ONE® is indicated for individuals with knee osteoarthritis who have inadequately responded to dietary, exercise, and over-the-counter pain management interventions.
ORTHOVISC® is an FDA-approved pharmaceutical-grade viscosupplement made of high molecular weight injectable HA. It consists of highly purified sodium hyaluronate (NaHA) in physiological saline.
ORTHOVISC® is administered via direct knee insertion to alleviate pain in patients experiencing joint inflammation.
DUROLANE® is a single-treatment HA therapy. It has a greater efficacy compared to SYNVISC ONE® and corticosteroids.
The solution is approved for managing symptomatic pain associated with mild to moderate osteoarthritis in the ankle, fingers, and toes.
There are many suppliers that you can buy orthopaedic injections wholesale from. But it’s crucial to obtain them from a reputable and dependable supplier. Contact out team at Medical Spa RX for guidance.