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Product Description

NUCLEOFILL™ SOFT PLUS is ideal for mild skin aging or early intervention, providing biorestructuring effects that are preventive and corrective. It is suitable for facial rejuvenation, improving elasticity, and reducing minor scars or wrinkles. Additionally, it is often used in combination treatments to enhance results in other skin therapies.

By stimulating the skin’s natural regenerative processes, NUCLEOFILL™ SOFT PLUS offers a long-lasting improvement in skin appearance and health.

NUCLEOFILL™ SOFT PLUS Indications for Use

NUCLEOFILL™ SOFT PLUS is a biostimulatory gel designed to rejuvenate and protect the skin. Composed of highly purified natural polynucleotides, it aims to improve skin quality by addressing issues such as dehydration, oxidative stress, and fine lines. This product activates bio-regeneration at various levels, including fibroblast stimulation, improving skin hydration, and enhancing skin elasticity. It is also effective in treating scars, such as acne and varicella marks, and stretch marks.

• Main Indications:
  • Dehydrated skin
  • Skin affected by oxidative stress
  • Asphyxiated skin
  • Scars from acne, chickenpox, or other skin conditions
  • Stretch marks

NUCLEOFILL™ SOFT PLUS Dosage Information

NUCLEOFILL™ SOFT PLUS comes in a 1.5 ml syringe, with the gel administered into the deep dermis or subcutaneous layers, depending on the desired treatment. The product is typically applied in a series of treatments.

• Application: Administer via dermal injections following the recommended protocols.
• Dosage: Generally 1-2 ml per session, depending on the area being treated.
• Frequency: It is recommended to have 2-3 treatment sessions spaced 2-4 weeks apart for optimal results.

NUCLEOFILL™ SOFT PLUS Side Effects and Precautions

The product is generally well-tolerated, with few reported side effects. However, as with any injectable treatment, some localized reactions may occur, including swelling, redness, bruising, or itching at the injection site. These effects are usually mild and resolve within a few days.

Precautions:

• Conduct a thorough patient assessment before application to ensure there are no contraindications.
• Avoid using the product in individuals with hypersensitivity to any of the components.
• It is not recommended for patients who are pregnant or breastfeeding.

NUCLEOFILL™ SOFT PLUS Clinical Studies and Real-World Outcomes

NUCLEOFILL™ SOFT PLUS has been shown to improve skin hydration, elasticity, and overall dermal structure through various clinical trials and real-world applications. The biostimulant effect stimulates collagen production and angiogenesis (formation of new blood vessels), leading to enhanced skin quality and a visible reduction in fine lines.

• Results: Patients typically see noticeable improvements after 2-3 sessions, with results lasting between 6-9 months depending on the individual’s skin condition and lifestyle.
• Key Findings: Studies highlight its effectiveness in reducing wrinkles, enhancing skin elasticity, and hydrating the skin for long-lasting effects.

NUCLEOFILL™ SOFT PLUS Drug Interactions

There are no known significant drug interactions with NUCLEOFILL™ SOFT PLUS. However, practitioners should avoid combining this treatment with certain energy-based devices (e.g., lasers or radiofrequency) within a short time frame unless recommended by specific protocols.

• Recommended Combinations: NUCLEOFILL™ SOFT PLUS can be safely combined with other aesthetic treatments like carboxytherapy, chemical peels, or hyaluronic acid fillers. When combined, it may enhance the rejuvenating effects of these treatments.

NUCLEOFILL™ SOFT PLUS Product Information

Supplied Equipment: The package includes a 1.5 ml syringe and two 30G needles for accurate and comfortable administration.

Polynucleotide concentration: NUCLEOFILL™ SOFT PLUS contains 2% polynucleotide gel, with a molecular weight of 2,500 kDa.

pH: Between 6.8 and 7.5.

Viscosity: Ranges from 28-43 Pa·s, depending on the formulation.