HYALGAN®

About Hyalgan Injection

HYALGAN® is a sterile, viscous solution containing sodium hyaluronate, a naturally occurring component of synovial fluid, with a molecular weight between 500,000 and 730,000 Daltons. Fidia Farmaceutici S.p.A. manufactures Hyalgan products, with HYALGAN® marking its US Food and Drug Administration (FDA) approval in 1997, and has since accumulated over 50 million injections globally.

This injectable treatment contains natural sodium hyaluronate extracted from rooster combs and is FDA-approved for osteoarthritis knee pain when conservative therapies fail to offer relief.

The first thing every doctor should keep in mind is that Hyalgan is a product, the use of which can lead to adverse occurrences or negative consequences if patients with contraindications use it. Therefore, it’s essential to learn more about this injection before giving it to everyone with osteoarthritis.

Hyalgan Indications and Contraindications

Hyalgan® is an injectable solution consisting of sodium hyaluronate, indicated for patients with knee osteoarthritis who experience persistent pain despite trying conservative management options and simple drugs like acetaminophen or NSAIDs.

Delivered directly into the knee joint, this treatment restores the viscous, shock-absorbing properties of synovial fluid, which can help reduce pain and improve joint function over a series of five weekly injections.

However, clinicians must observe several contraindications to ensure patient safety:

• Patients with known hypersensitivity to sodium hyaluronate or any Hyalgan products
• Active infection or skin disease at or near the injection site, to avoid septic arthritis
• Signs of acute inflammation in the target joint, such as effusion or redness, especially in inflammatory arthritis
• Allergies to avian proteins, feathers, or egg products, since Hyalgan is derived from rooster combs
• Individuals under 18 years old, pregnant or lactating women—safety in these populations remains unestablished

In clinical trials, the most frequent adverse events included transient injection-site pain, swelling, bruising, rash, and headaches—effects that did not increase in severity with repeated treatment cycles.

Overall, Hyalgan offers a well-characterized option for managing knee osteoarthritis pain, provided that proper patient selection and clinician oversight are in place.

Hyalgan for Knee Osteoarthritis: Mechanism of Action and Protocol

Hyalgan® is an intra-articular injectable solution of sodium hyaluronate, used as a lubricant and shock absorber in the knee joint to alleviate pain from knee osteoarthritis. It supplements the diminished synovial fluid, improving the elasticity and viscosity of the joint environment. This enhanced lubrication enables the joint surfaces to glide more smoothly, reducing friction and protecting damaged cartilage.

Patients follow a regimen of five weekly injections, each restoring the natural cushioning effect necessary for joint function. Clinical studies have shown that even a partial series can provide long-lasting relief, with effects commonly lasting up to six months.

By restoring synovial fluid properties, Hyalgan acts as a non-surgical treatment option for knee osteoarthritis, reducing reliance on oral drugs and enhancing overall management of chronic joint pain.

It can offer the following key benefits:

• Provides a viscoelastic buffer to absorb joint stress
• Reduces day-to-day pain with weekly injections
• Offers relief up to six months per treatment cycle

Hyalgan delivers scientifically backed relief through viscosupplementation, addressing the core mechanics of osteoarthritis for improved joint health. Furthermore, we’ve made a dedicated article about Hyalgan Prescribing Information.

Potential Hyalgan Side Effects

Hyalgan, an injectable product containing hyaluronic acid, is designed to function as a lubricant and shock absorber in the knee joint to relieve symptoms of knee osteoarthritis.

While it is generally well tolerated, patients may experience some adverse effects, particularly around the injection site. These local reactions can include redness, swelling, bruising, stiffness, and mild joint discomfort. Such responses are typically temporary and resolve on their own without intervention.

In addition to site-specific effects, Hyalgan may occasionally lead to systemic side effects. Patients have reported symptoms such as headache, nausea, back pain, stomach discomfort, fatigue, and cold-like symptoms.

Other rare effects include numbness or tingling sensations, itching, and skin irritation. It is important for healthcare providers to inform patients about potential risks before beginning treatment.

Each Hyalgan dose is typically administered using pre-filled syringes, which allows for precise delivery into the affected knee joint. If any side effects worsen or persist, patients should promptly consult their medical provider for further evaluation.

Sourcing From Canada/USA: How Much Does It Cost?

Hyalgan is manufactured in the United States by Fidia Pharmaceuticals and is widely available through authorized retailers in North America. Patients and medical providers can buy Hyalgan online through licensed distributors offering FDA-approved formulations. Each product package typically contains five prefilled syringes, with each 2 mL injection containing 20 mg of sodium hyaluronate, the sodium salt form of hyaluronic acid used to treat knee osteoarthritis. This viscoelastic knee therapy helps restore joint lubrication, improving mobility and reducing pain in affected individuals.

Pricing may vary depending on the distributor, region, and shipping destination. However, due to the product’s widespread availability, Hyalgan remains competitively priced, making it an affordable option for patients seeking long-term relief from the symptoms of knee osteoarthritis. Always ensure that the package insert is included for dosage, administration, and safety guidance.

Why Is Medical Spa RX the Best Place For Shopping Online

Sourcing Hyalgan online has become significantly easier with trusted suppliers like Medical Spa RX, a reputable distributor of medical supplies and meds for aesthetic and therapeutic purposes. The platform caters to licensed professionals treating knee osteoarthritis, helping them offer cost-effective care to patients. Customers can quickly order original Hyalgan products sourced directly from manufacturers, ensuring both authenticity and safety.

Reasons why Medical Spa RX stands out as the ideal choice:

• A wide base of repeat customers across various medical fields;
• Free shipping for orders over $500, helping clinics save on logistics;
• Years of proven experience in distributing aesthetic and therapeutic medical supplies;
• A frequently updated product catalog, ensuring access to the latest treatments;
• Convenient ordering options — online or via phone;
• Bulk purchasing options, with discounts available for orders of five or more Hyalgan packs.

For healthcare providers seeking high-quality knee osteoarthritis solutions, Medical Spa RX combines reliability, cost-effectiveness, and ease of access.

Buy Hyalgan Wholesale At Medical Spa RX

Many retailers limit bulk orders, but Medical Spa RX allows licensed professionals to purchase Hyalgan in large quantities without restrictions.

Whether you need a few packs or the store’s full inventory, you can place wholesale orders easily. This flexibility supports clinics and practices managing multiple patients with knee osteoarthritis by ensuring they never run short on treatment stock.

• No cap on bulk purchases
• Full inventory access for high-volume buyers
• Convenient ordering system for medical professionals

Cost per Unit in Bulk Purchase

Medical Spa RX offers significant savings when you order Hyalgan in bulk. While stock levels vary by manufacturer, the platform offers tiered pricing based on order size.

The more you purchase, the lower the cost per unit. Clinics that order 5–10 packs receive discounted pricing, while those who buy over 21 packs may benefit from up to a 10% discount per unit.

Source Hyalgan Online with License

To ensure patient safety and product authenticity, Medical Spa RX only sells Hyalgan to verified healthcare professionals. Before placing an order, medical practitioners must provide valid credentials. This policy helps maintain ethical standards and ensures that buyers receive genuine, approved medical products.

Medical Spa RX is also certified by relevant authorities to distribute cosmetic and therapeutic products online, reinforcing its status as a trusted supplier.

• License verification required before purchase
• Sales limited to certified medical professionals
• Fully authorized distributor of medical supplies and injectable treatments

FAQs

Can I order this product online?

Yes, you can order Hyalgan online from an official distributor of the company, such as Medical Spa RX.

What are the license requirements?

Hyalgan injections can only be administered by physicians who have thoroughly reviewed the full prescription information, including indications, contraindications, safety warnings, precautions, and potential adverse reactions, and have sufficient injection experience.

Is it legal to purchase products like this from overseas?

Yes, it is. The majority of manufacturers have their distributors on several continents, so medical products are shipped worldwide. The only thing to check is proper storage conditions and approval by a manufacturer’s pack.

How do I acquire this product as a provider?

Any client can place an order in Medical Spa RX in two simple ways: by contacting the customer support team by phone or by creating an account on the site.

Can nurse practitioners purchase this product?

If a nurse has received a license that allows her to administer Hyalgan treatments, she can also purchase this solution.