Osteoarthritis (OA) affects millions worldwide, with the knee being a common target. Studies have found that viscosupplementation, a treatment involving hyaluronic acid (HA) injections, is a promising option for patients with knee OA. HA not only restores joint fluid viscoelasticity but also downregulates pro-inflammatory factors.

Durolane is one such viscosupplement explicitly designed for knee osteoarthritis. Known for its single-injection formulation and high molecular weight, Durolane provides long-lasting relief and convenience. 

This article will review Durolane knee injections, exploring patient testimonials and experiences to provide a comprehensive overview of its benefits and effectiveness.

Key Takeaways

  • Durolane knee injection is a treatment for osteoarthritis that aims to provide pain relief and improved mobility.
  • Patient reviews, and clinical feedback on Durolane knee injections highlight positive and negative experiences.
  • Factors such as the severity of osteoarthritis, injection technique, and post-treatment care can influence patient outcomes.
  • Clinical studies and patient testimonials provide valuable insights into the effectiveness of Durolane compared to other knee injection treatments.

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What is Durolane Knee Injection?

Knee pain.

Durolane is a hyaluronic acid injection used to treat knee osteoarthritis, which often results in joint discomfort and limited mobility. It is specifically designed to enhance arthritis relief by lubricating the knee joint.

Durolane’s manufacturer, Bioventus, utilizes hyaluronic acid, a substance naturally found in the synovial fluid of joints, to help reduce pain and improve movement. This injection mimics the synovial fluid, providing lubrication and acting as a cushion, facilitating smoother joint movement.

This treatment method, known as viscosupplementation therapy, targets joint inflammation by offering additional cushioning and support. Durolane can significantly ease walking and moving for individuals with knee osteoarthritis, improving overall quality of life.

Patient Reviews of Durolane Knee Injection

Knee injection.

Durolane knee injections have become a key player in managing knee osteoarthritis. They offer a promising solution for pain relief and joint mobility.

  • “In the queue for a hip replacement but started looking for an alternative. Took an ultrasound-guided hip joint injection a month ago, 3ml of Durolane. The pain increased for the first week and a half, but now almost no pain, very pleased and hope it lasts six months. I’m getting over my limp, building up atrophied muscles, and resuming my regular activities like long walks and pickleball”
  • “I’m glad I didn’t read the reviews before having this injection or I might never have tried it. My left knee is bone on bone and I tore the meniscus on Christmas Eve 2020. My knee is in such bad shape the ortho surgeon wouldn’t do a repair – said it wouldn’t be worth it without replacing it totally. He suggested trying the Durolane injection and I did. It didn’t do anything for the first almost 3 weeks but then one day I realized I didn’t need my crutches anymore and could walk without pain for the first time in about 2 years. Yes, the injection is very uncomfortable. And yes, I feel crappy afterwards and my knee is swollen, painful and stiff. But I had 6 pretty much pain free months before needing my second one just this week. I’m 53 and if this can help me put off knee replacement then I will be a happy camper.”

While many seek relief from Durolane knee injections, many face challenges. Some users report adverse outcomes, highlighting the complexity of treating knee osteoarthritis.

  • Many people experience extreme pain after the injection, which makes walking hard.
  • Some folks find no relief from their joint pain, even after getting the treatment.
  • Infections at the injection site have been reported, adding to the discomfort and risk.
  • A few individuals have increased knee swelling, making mobility more challenging.
  • Several patients note that their overall knee health felt worse post-treatment.
  • Comparisons show some other knee joint injections may cause fewer adverse reactions than Durolane.
  • Patients often share stories about having to seek additional treatments to manage the side effects of Durolane.
  • Feedback suggests that for some, Durolane does not live up to expectations for easing knee arthritis symptoms.
  • The severity of osteoarthritis, in some instances, may influence the lack of positive results from Durolane injections.
  • Techniques used during injection can vary, leading to different experiences and sometimes adverse outcomes.

Factors Influencing Patient Outcomes

Knee pain.

Osteoarthritis severity dramatically affects how well patients do after getting Durolane knee injections. Some people with mild or moderate osteoarthritis see good results, like less pain and better movement. Yet, for those with severe disease, the outcome might be less remarkable. 

How well someone gives the Durolane knee injection is also crucial. A good technique can mean the difference between relief and discomfort. Doctors must choose the right spot on the knee to inject and apply just enough pressure. This skill helps avoid side effects like swelling or pain at the injection site. Adequately done, injections can lead to better mobility and less pain for patients.

Additionally, posttreatment care plays a critical role in the outcomes for patients with knee osteoarthritis following Durolane injections. The severity of osteoarthritis affects how long the relief from injection lasts.

Clinical Studies and Patient Testimonials

Studies on Durolane show mixed results. With an average rating of 4.5 out of 10 from 249 reviews on Drugs.com, patient feedback varies widely. About 35% have reported positive experiences, highlighting decreased pain and improved mobility as critical benefits.

However, a more significant portion, 58%, shared negative experiences. These individuals did not see the improvement they hoped for in pain management or mobility post-treatment. Such outcomes underscore the importance of considering individual factors like the severity of osteoarthritis and the technique used during injection, which can significantly influence patient satisfaction levels.

TreatmentNumber of InjectionsDuration of Pain ReliefSide EffectsPatient Satisfaction and Effectiveness
Durolane (NASHA)Single injectionUp to 6 monthsInjection site pain, swelling, skin reactionsHigh satisfaction with pain relief and mobility improvement; effectiveness supported by clinical trials
Hylan G-F 20 Single injectionInjection site pain, swelling, stiffness, skin reactionsHigh satisfaction with multi-dose regimens, effective for pain management and joint function  
Other HA InjectionsMultiple injections (usually 3-5)Generally less than six monthsInjection site pain, swelling, skin reactions

Conclusion

Durolane knee injection attracts varied responses. Some individuals experience significant comfort and enhanced mobility, while others encounter increased discomfort or no alteration in their condition.

The outcomes appear to be contingent on the individual’s status and body’s response. Reading and checking reviews aids individuals in making optimal decisions about their knee issues.

FAQs

1. What are Durolane knee injections?

Durolane knee injections are a type of treatment for knee pain. They’re designed to provide relief and improve mobility.

2. How do people review the effectiveness of Durolane knee injections?

Though individual results may vary, most reviews and testimonials indicate that Durolane knee injections can be quite effective in relieving pain and improving mobility.

3. Are there any negative reviews or testimonials about Durolane knee injections?

Yes, while many find relief with these treatments, some individuals report minimal improvement or side effects, such as temporary discomfort at the injection site.

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References

Peck, J., Slovek, A., Miro, P., Vij, N., Traube, B., Lee, C., Berger, A. A., Kassem, H., Kaye, A. D., Sherman, W. F., & Abd-Elsayed, A. (2021, July 10). A comprehensive review of viscosupplementation in osteoarthritis of the knee. Orthopedic Reviews, 13(2). https://orthopedicreviews.openmedicalpublishing.org/article/25549-a-comprehensive-review-of-viscosupplementation-in-osteoarthritis-of-the-knee

Drugs.com. (n.d.). Durolane (sodium hyaluronate) user reviews (page 2). Retrieved July 9, 2024, from https://www.drugs.com/comments/sodium-hyaluronate/durolane.html?page=2

Carney, G., Harrison, A., & Fitzpatrick, J. (2021). Long-Term Outcome Measures of Repeated Non-Animal Stabilized Hyaluronic Acid (Durolane) Injections in Osteoarthritis: A 6-Year Cohort Study with 623 Consecutive Patients. Open access rheumatology: research and reviews, 13, 285–292. https://doi.org/10.2147/OARRR.S331562