Facial treatments have seen a significant surge in popularity, with the American Academy of Facial Plastic and Reconstructive Surgery reporting a 40% increase in procedures in 2021. This rise is attributed to the growing desire for aesthetic enhancements and the influence of social media. Non-surgical treatments, in particular, have become a go-to for many seeking quick and effective results without the downtime associated with surgery.

Nabota, also known as Jeuveau, is a botulinum toxin type A developed by Daewoong Pharmaceutical Co., Ltd. It is FDA-approved for treating moderate to severe frown lines. Nabota offers a reliable alternative to traditional Botox, providing similar efficacy and duration. Its popularity continues to grow, thanks to its effectiveness in reducing wrinkles and improving facial aesthetics. 

This article will explore the science behind before-and-after photos, dissecting their impact and potential pitfalls. We’ll then delve into the specifics of Nabota, discussing its mechanism of action, administration, and expected results.

Key Takeaways

  • Nabota is a botulinum toxin Type A used to smooth facial lines and reduce wrinkles and fine lines.
  • Nabota works by blocking nerve signals to targeted muscles, temporarily reducing muscle activity and softening the appearance of wrinkles.
  • Nabota’s benefits include quick treatment times, minimal discomfort, and effective results with a high safety profile.
  • It treats both cosmetic concerns (such as wrinkles) and medical conditions (including muscle spasticity and excessive sweating).
  • Nabota treatments involve consultation, precise injections, and follow-up care to ensure optimal results.
  • Patient testimonials and clinical data consistently show positive outcomes with long-term maintenance options available.

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Nabota Before and After Photos

Before and after facial treatment.

Image Courtesy of Altos Klinika

The face shows signs of aging, including fine lines, wrinkles, and volume loss in critical areas like the cheeks and under the eyes. Skin texture appears dull and uneven, with noticeable sagging around the jawline and cheeks. The overall expression may look tired or worn.

Following facial rejuvenation, the skin appears smoother and more radiant, significantly reducing fine lines and wrinkles. Volume is restored to the cheeks and under-eye areas, creating a more youthful and lifted appearance. The jawline is more defined, and the facial expression looks refreshed and revitalized.

Before and after facial treatment.

Image Courtesy of Altos Klinika

The face exhibits visible signs of sun damage, such as dark spots and uneven pigmentation. There may be a loss of skin elasticity, leading to sagging and a lack of firmness, particularly around the mid-face and neck areas. The skin may also appear dehydrated and lackluster.

Post-treatment, the face is noticeably rejuvenated, with a brighter and more even complexion. Dark spots and pigmentation issues are significantly reduced, and skin elasticity is improved, giving the face a firmer and more lifted appearance. The skin looks hydrated, glowing, youthful, and refreshed overall appearance.

Understanding Nabota and Its Benefits

Nabota is a type of botulinum toxin Type A. Doctors use it to smooth facial lines by injecting it into facial muscles. Produced by the South Korean pharmaceutical company Daewoong, Nabota is designed for both cosmetic and therapeutic applications.

Nabota works by blocking the neurotransmitter acetylcholine at the neuromuscular junction. This blockade prevents the muscle from receiving signals from the nerve, temporarily paralyzing the muscle. 

When injected into facial muscles, Nabota softens the appearance of wrinkles and fine lines caused by repeated muscle contractions. It also reduces excessive muscle activity, helping with medical conditions such as spasticity.

Benefits of Nabota Treatments

  • Quick and Minimally Invasive: Nabota injections are quick, usually completed within 10-20 minutes, and require no anesthesia, although a numbing cream can be applied to minimize discomfort. Following the guidelines for proper Nabota reconstitution helps with this process. 
  • Effective Results: Patients typically see results within a few days, with the full effect visible in about one to two weeks. The results are natural-looking, enhancing facial aesthetics without compromising expressiveness.
  • High Safety Profile: Nabota is well-tolerated and has few side effects, making it a reliable option for cosmetic and medical treatments.
  • Versatile Uses: Besides cosmetic applications, Nabota treats various medical conditions, relieving symptoms that impact quality of life.

Conditions Treated by Nabota

Facial treatment.
  • Wrinkles and Fine Lines: Wrinkles and fine lines appear as we age. They form because our facial muscles move a lot. Nabota, a type of botulinum toxin Type A, helps with these signs of aging. Doctors inject it into the facial muscles.
  • Medical Conditions such as Cervical Dystonia and Spasticity: Nabota helps people with cervical dystonia and spasticity. Cervical dystonia makes neck muscles contract, causing pain and odd head positions. Spasticity tightens muscles more than usual, making movement hard.
  • Excessive Sweating (Hyperhidrosis): Excessive sweating can make life challenging. People sweat a lot, even when it’s not hot. Doctors use Nabota to treat hyperhidrosis. The treatment stops the sweat glands from working too hard.

The Nabota Treatment Process

  • Consultation and Assessment: Before getting Nabota injections, doctors talk with patients to understand their needs. They look at the skin and decide where to put the injections. Doctors explain how Nabota works and what it does for wrinkles.
  • Administration of Nabota Injections: A doctor gives Nabota injections. They use a small needle to inject Nabota into facial muscles, where wrinkles appear. Doctors target these spots to smooth lines. It takes skill to do this right. The doctor looks at each face closely. Then, they decide where to inject Nabota for the best results. Patients see changes in 1-2 weeks after getting the shots.
  • Posttreatment Care and Follow-up: After getting Nabota injections, patients should follow care instructions to see the best results. It’s important to avoid touching or massaging the treated area for a few hours. This helps prevent the toxin from spreading to other muscles.

Patient Testimonials and Clinical Data

Clinical studies have demonstrated Nabota’s efficacy in treating glabellar frown lines. A phase 4 clinical study involving 42 subjects found that 85.4% of participants showed improvement in glabellar frown lines at maximum frown just two days after administration.

Additionally, 51.2% of subjects exhibited improvement in glabellar lines at rest within the same timeframe. The study concluded that Nabota is both safe and effective for this application, with no severe adverse events reported.

The long-term results of Nabota treatments are promising, with many patients experiencing sustained improvements. Regular maintenance sessions are recommended to maintain the desired aesthetic outcomes.

Clinical data suggests that the effects of Nabota can last several months. Patients typically return for follow-up treatments every 3 to 6 months to maintain their results. This consistent maintenance helps ensure the skin remains smooth and wrinkle-free.

Conclusion

Nabota is a versatile botulinum toxin type A product that offers effective solutions for both cosmetic and medical concerns. Whether you’re looking to reduce the signs of aging or manage a medical condition like cervical dystonia or hyperhidrosis, Nabota provides a safe, minimally invasive treatment option with proven results.

With positive patient testimonials and robust clinical data supporting its use, Nabota continues to be a trusted choice for many seeking to enhance their appearance or alleviate discomfort from medical conditions.

FAQs

1. What makes Nabota different from other botulinum toxin products like Botox?

Nabota is a botulinum toxin type A product with high purity and consistency, which can lead to faster results and potentially longer-lasting effects. Its manufacturing process minimizes unnecessary proteins, possibly reducing the risk of developing resistance.

2. How long do the effects of Nabota last?

The effects of Nabota typically last three to four months, depending on the individual and the area treated. After this period, muscle activity gradually returns, and the results may fade. Regular treatments can help maintain the desired effects.

3. Is the Nabota treatment painful?

Nabota injections are generally well-tolerated, with most patients experiencing only mild discomfort. 

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References

American Academy of Facial Plastic and Reconstructive Surgery. (2022, February 17). AAFPRS 2021 annual survey reveals pandemic surge in facial plastic surgery. AAFPRS. https://www.aafprs.org/Media/Press_Releases/2021%20Survey%20Results.aspx

Dr. Avaliani. (n.d.). Jeuveau (Nabota): Botox and fillers. Retrieved August 10, 2024, from https://www.dravaliani.com/cosmetic-treatments/botox-fillers/jeuveau-nabota/ 

Kim, D. Y., & Kim, J. M. (2018). Safety and efficacy of prabotulinumtoxinA (Nabota®) injection for cervical and shoulder girdle myofascial pain syndrome: A pilot study. Toxins, 10(9), 355.