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Product Description

BELLAST® PLUS Product Overview

BELLAST® PLUS is an injectable hyaluronic acid (HA) dermal filler formulated to treat moderate to deep facial wrinkles and volume loss. Designed with cross-linked hyaluronic acid of non-animal origin, BELLAST® PLUS enhances skin hydration, firmness, and elasticity by naturally restoring volume and filling wrinkles. This formulation leverages High Concentration Cross-Linking (HCXL) Technology, which provides a filler with high purity, ideal viscosity, and elasticity, enhancing durability and biocompatibility. BELLAST® PLUS is suitable for areas of the face prone to volume loss, such as the nasolabial folds and marionette lines.

Key Features:

• Hyaluronic Acid Concentration: 20 mg of cross-linked HA
• Cross-Linking Technology: HCXL technology for enhanced cross-linking efficacy
• Packaging: 1.0 ml syringe, sterile and single-use
• Duration: Results last up to 6-12 months

BELLAST® PLUS Indications for Use

BELLAST® PLUS is designed for volume restoration and moderate-to-deep wrinkle correction. It is ideal for patients experiencing age-related volume loss and deep lines, providing long-lasting improvements and a youthful appearance.

Primary Indications:

• Nasolabial Folds: Reduces the appearance of deep lines from the nose to mouth.
• Marionette Lines: Smooths lines around the mouth to restore facial contours.
• Cheek Volume: Adds fullness to cheeks to address age-related sagging.
• Moderate to Severe Wrinkle Reduction: Fills in and smooths deeper facial lines.

BELLAST® PLUS Dosage Information

BELLAST® PLUS is administered through precise injection techniques, allowing practitioners to achieve optimal volume restoration and wrinkle reduction.

Treatment Protocol:

• Injection Volume: 1 ml per treatment session, customized based on wrinkle severity and patient goals.
• Injection Depth: Mid to deep dermis, enabling stable support and volume for larger wrinkles.
• Frequency: Typically a single session, with potential follow-up treatments every 6-12 months depending on patient needs.

BELLAST® PLUS Side Effects and Precautions

BELLAST® PLUS is generally well-tolerated due to its biocompatible formula. Side effects are typically mild and resolve shortly after treatment.

Common Side Effects:

• Redness and Swelling: Transient swelling or redness at the injection site, resolving within 1-3 days.
• Bruising: Minor bruising may occur, particularly in sensitive areas.
• Mild Discomfort: Temporary tenderness is common, but typically subsides within a few days post-treatment.

Precautions:

• Aseptic Injection Technique: Ensures safety and minimizes infection risk.
• Contraindications: Not suitable for patients with autoimmune diseases, allergies to hyaluronic acid, or active skin infections.
• Pregnancy and Breastfeeding: Not recommended for use during pregnancy or breastfeeding.
• Post-Treatment Care: Patients should avoid intense physical activity and sun exposure for at least 24 hours following treatment.

BELLAST® PLUS Clinical Studies or Real-World Outcomes

Clinical studies on BELLAST® PLUS demonstrate its effectiveness in reducing wrinkle depth and increasing facial volume. The filler’s advanced formulation and cross-linking technology contribute to its long-lasting results and high patient satisfaction.

Key Findings:

• Wrinkle Depth Reduction: Patients experienced a significant reduction in wrinkle severity after treatment, with visible improvements in the Wrinkle Severity Rating Scale (WSRS) within 3-6 months.
• Volume and Firmness Maintenance: The product retained volume in treated areas for up to 6-12 months, depending on individual factors such as skin type and lifestyle.
• High Satisfaction Rates: A majority of patients reported satisfaction with the filler’s natural feel and appearance, noting enhanced facial contours and smoother skin texture.

Clinical Observations:

• Durability and Stability: Patients maintained a smoother and more youthful appearance for 6-12 months post-treatment, particularly in high-mobility areas such as the nasolabial folds.
• Minimal Adverse Effects: No severe adverse events were reported in clinical trials, with only mild side effects such as temporary redness or tenderness.

BELLAST® PLUS Composition and Active Ingredients

BELLAST® PLUS is composed of 20 mg/ml cross-linked hyaluronic acid using HCXL Technology, a unique formulation that optimizes the filler’s viscosity and elasticity.

Key Ingredients:

• Cross-Linked Hyaluronic Acid (20 mg/ml): Provides volume and hydration, supporting collagen synthesis for a more resilient skin structure.
• High Concentration Cross-Linking Technology (HCXL): Creates a pure, stable HA gel that reduces the potential for migration and improves durability in facial tissue.

BELLAST® PLUS Drug Interactions

BELLAST® PLUS is a localized injectable with minimal systemic absorption, which reduces the likelihood of drug interactions.

Important Considerations:

• Combination with Other Aesthetic Treatments: Can be used alongside other biostimulatory and filler treatments, though a two-week interval is recommended between different products.
• Anticoagulants: Patients on blood thinners should be aware of the increased potential for bruising.
• Immunosuppressive Therapy: Use cautiously in patients undergoing immunosuppressive therapy due to elevated infection risks.