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HArmonyCA™ Product Description

HArmonyCA™ is a dual-effect hybrid injectable combining hyaluronic acid (HA) for an immediate lifting effect and calcium hydroxyapatite (CaHA) for long-lasting collagen stimulation. This dermal filler is designed for facial soft tissue augmentation and is injected into deep dermal and sub-dermal layers. The inclusion of lidocaine ensures a more comfortable treatment experience by reducing pain during administration.

Key details:

• Combines HA and CaHA for dual benefits.
• Intended for adults over 18 years old.
• Addresses volume loss and structural support deficiencies in aging skin.

HArmonyCA™ Key Features and Benefits

HArmonyCA™ stands out with its ability to provide both immediate and long-lasting effects:

• Immediate lifting effect from hyaluronic acid.
• Gradual collagen production stimulation by calcium hydroxyapatite.
• Enhances skin architecture for a natural and youthful appearance.
• Delivers high patient satisfaction with an average 4.1/5 rating and 91.6% reporting improvement in treated areas.

Clinical outcomes demonstrate:

• Results lasting between 12 to 36 months based on collagen stimulation and filler properties.
• Improved general appearance and high likelihood of treatment repetition up to 19 months post-procedure.

HArmonyCA™ Composition

The product contains:

• Hyaluronic acid (HA) for hydration and immediate volumizing effects.
• Calcium hydroxyapatite (CaHA) microspheres to stimulate collagen production over time.
• Lidocaine (local anesthetic) for reduced pain during injections.

HArmonyCA™ Intended Purpose / Indications

HArmonyCA™ is indicated for:

• Facial volume restoration, targeting areas such as the cheeks, chin, and jawline.
• Improvement in skin elasticity and structure.
• Addressing early signs of aging, including fine lines and sagging.

HArmonyCA™ Injection and Treatment Areas

Recommended treatment areas:

• Cheeks, jowls, and chin for volume and contouring.
• Other facial zones based on patient-specific needs as determined by a healthcare professional.

Injection depth:

• Injected into deep dermal and sub-dermal layers to optimize collagen stimulation and volumizing effects.

HArmonyCA™ Reconstitution and Preparation Guidelines

The product is supplied pre-filled in syringes and does not require reconstitution. Before use:

• Inspect for damage or leakage.
• Maintain aseptic technique during preparation.
• Ensure all tools, including needles, meet clinical standards.

HArmonyCA™ Administration and Dosage

Administration:

• Performed by trained professionals using standard injection techniques.
• Typical injection volume per treatment session varies based on patient needs.

Dosage:

• For optimal results, 0.1 to 0.5 mL per injection point is recommended.
• Total treatment volume is typically around 7.4 mL, distributed across the cheeks, jowls, and chin.

HArmonyCA™ Storage Instructions

Storage conditions:

• Maintain at 2–25°C.
• Protect from direct sunlight and avoid freezing.

HArmonyCA™ Contraindications

The product is contraindicated in:

• Patients with allergies to HA or CaHA.
• Presence of active skin infections or inflammatory conditions near the treatment site.
• Pregnant or breastfeeding individuals.
• Patients with autoimmune diseases or compromised immune systems.

HArmonyCA™ Precautions and Warnings

Important considerations:

• Avoid injection into vascular areas to minimize the risk of intravascular complications.
• Do not combine with other dermal treatments during the same session.
• Ensure thorough patient consultation to assess medical history.

HArmonyCA™ Post-Treatment Care

Aftercare recommendations:

• Avoid makeup application for 24 hours.
• Limit UV exposure and extreme temperature environments for at least one week.
• Gently massage the treated area if nodules or irregularities appear.

HArmonyCA™ Side Effects and Adverse Reactions

Common side effects:

• Redness, swelling, pain, or tenderness at the injection site.
• Itching or bruising, typically resolving within 24–48 hours.

Rare but serious reactions:

• Persistent swelling or nodules.
• Seek immediate medical attention for severe or unlisted side effects.

Reporting:

• Adverse reactions can be reported via the Yellow Card Scheme in the UK or directly to Allergan.

HArmonyCA™ Patient Eligibility

Suitable candidates:

• Adults aged 18 years or older.
• Patients seeking long-term improvements in facial volume and elasticity.

Not suitable for:

• Individuals with underlying health conditions affecting the immune system.
• Patients on anticoagulant therapy or with a history of severe allergic reactions.

HArmonyCA™ Follow-Up and Maintenance

Follow-up:

• Regular check-ups ensure optimal outcomes.
• Touch-ups may be required after 12–18 months to maintain effects.

HArmonyCA™ Manufacturer and Regulatory Information

Manufactured by:

• Allergan Aesthetics, an AbbVie company.

Regulatory compliance:

• Certified under CE marking for safety and performance in the EU.
• Marketed with rigorous post-marketing surveillance for continued safety assurance.

HArmonyCA™ FAQ

Discuss with your healthcare provider for personalized treatment planning.

What is the dual effect of HArmonyCA™?

It combines immediate lift with HA and long-term collagen stimulation with CaHA.

How long do results last?

Effects can last from 12 to 36 months, depending on individual factors.

Are there any specific age restrictions?

Suitable for patients aged 18 years and above.

Can HArmonyCA™ be combined with other treatments?