$195.00
Group Buy Price: $192
brand:
REVANESSE®
manufacturer:
Prollenium Medical Technologies Inc
active substances:
HYALURONIC ACID, MANNITOL
strength:
14mg/ml
pack size:
2 x 1.2ml Pre-Filled Syringes, 4x 30G 1⁄2" Needles
Revanesse® Pure™+ is indicated for both cosmetic and medical applications. On the cosmetic side, it is used for the treatment of facial wrinkles, volume restoration, lip enhancement, and skin hydration. For medical purposes, it is recommended for correcting soft tissue deficiencies and deformities that are caused by medical conditions or trauma. The product is primarily aimed at individuals requiring treatment for lipoatrophy or lipodystrophy, especially for those with HIV.
The product is designed for intradermal use, meaning it is injected into the dermis or mucous membrane of the lips. Only qualified medical professionals should administer this product, and it must be done under sterile conditions to avoid complications. The filler comes in a pre-filled syringe with a hyaluronic acid concentration of 14 mg/ml and lidocaine 3 mg/ml for pain relief. Physicians should ensure that the product is room temperature before use and must be aware that improper administration may lead to serious side effects.
Like any injectable cosmetic product, Revanesse® Pure™+ has potential side effects. Patients should be informed of possible reactions that may occur either immediately or after some time. The most common side effects include redness, swelling, pain, itching, and discoloration at the injection site. These reactions typically resolve within one week. More serious complications include nodules, induration, and in rare cases, necrosis and granulomas. The document stresses that all patients must be carefully monitored and informed of the potential risks, including allergic reactions.
The leaflet includes a risk assessment for lidocaine, limiting the annual dose to 20 ml per 60 kg of body weight. Beyond this, no safety studies are available to support higher dosages. The manufacturer advises caution with specific patient populations, including those under 18 years old or over 65 years old, as well as individuals with bacterial or viral infections. While real-world applications show a low rate of complications, patients should always report inflammatory reactions that last beyond a week to ensure proper management.
The hyaluronic acid in Revanesse® Pure™+ is incompatible with quaternary ammonium salts like benzalkonium chloride. Therefore, it is crucial that this product does not come into contact with medical devices that have been exposed to these substances. Patients on medications like aspirin, anti-inflammatory drugs, or high doses of Vitamin E are at a greater risk of bruising or bleeding after the injection. The document advises avoiding use in high-risk areas like the glabellar and nose regions, as there have been cases of vascular embolization and blindness. Additionally, patients should avoid prolonged sun exposure, UV rays, and extreme heat or cold until the redness and swelling have subsided.
The product should be injected slowly and with minimal pressure to avoid complications. If the skin blanches (turns white), the injection should be stopped immediately, and the area should be massaged until normal color returns. Before starting the injection, a small drop of product should be visible at the needle’s tip, ensuring proper flow and pressure control. Only practitioners with specialized training in filling facial wrinkles and volume restoration should administer Revanesse® Pure™+.
The document emphasizes that precision is critical to avoid vascular complications and tissue damage. Medical professionals must be trained to handle rare but serious adverse events like blindness or stroke, which have occurred when the product was mistakenly injected into blood vessels.
In conclusion, Revanesse® Pure™+ is a versatile, hyaluronic acid-based filler for both cosmetic and medical uses, but its administration requires strict adherence to guidelines, careful patient screening, and experienced medical professionals to ensure safety and effectiveness.
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