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STYLAGE® XL BI-SOFT® Indications for Use

STYLAGE® XL BI-SOFT® is an injectable hyaluronic acid-based dermal filler designed for the restoration or augmentation of facial volume. It is indicated for treating volume loss and creating facial contour by injecting into the deep dermis or subcutaneous tissue.

• Restoration of facial volume: Particularly useful for areas affected by aging, such as cheeks, temples, and jawline.
• Facial contouring: Helps in shaping facial contours to achieve a more youthful appearance.
• Hyaluronic acid gel: Cross-linked hyaluronic acid with mannitol as an antioxidant, providing longer-lasting results.

STYLAGE® XL BI-SOFT® Dosage Information

The dosage of STYLAGE® XL BI-SOFT® varies depending on the area being treated and the patient’s individual characteristics. It is provided in 1 ml pre-filled syringes, and it is recommended to avoid overcorrection.

• Recommended dose: Up to 2 ml per treated area in a single session.
• Maximum dose per year: 20 ml of cross-linked hyaluronic acid per individual.
• Frequency of injections: One to two sessions for initial correction, with follow-up touch-up sessions to maintain desired effects.

STYLAGE® XL BI-SOFT® Side Effects and Precautions

Patients may experience various side effects, ranging from mild to severe, following the administration of STYLAGE® XL BI-SOFT®. Practitioners must discuss potential adverse effects with patients and obtain informed consent prior to treatment.

• Common Side Effects:
  • Inflammatory reactions: Redness, swelling, or erythema at the injection site, which typically resolves within a week.
  • Bruising and hematomas: May occur at the injection site.
  • Nodules or indurations: Lumps or hard areas under the skin can develop, especially with overcorrection.
• Severe Side Effects:
  • Intravascular injection risks: Can cause vascular occlusion, leading to necrosis, blindness, or skin complications.
  • Infection: Local infections, including herpes reactivation, may occur if patients have a history of herpes.

Precautions:

• Avoid using STYLAGE® XL BI-SOFT® in patients with autoimmune diseases, pregnant or breastfeeding women, or those with known hypersensitivity to hyaluronic acid or lidocaine.
• Do not inject in areas with thin skin, such as the periorbital region or in patients prone to hypertrophic scars.
• Patients should avoid aspirin, NSAIDs, or anticoagulants one week prior to injection to  

STYLAGE® XL BI-SOFT® Clinical Studies or Real-World Outcomes

STYLAGE® XL BI-SOFT® has been tested and shown to provide significant facial volume restoration, with results lasting 12-18 months depending on the patient’s skin type and the area treated. Clinical outcomes demonstrate:

• Effective volume restoration: Particularly in areas such as the cheeks, with noticeable improvement after one or two sessions.
• High patient satisfaction: Due to both the long-lasting results and the pain-relieving properties of lidocaine, included in some versions of the product.

Patients undergoing treatment generally report improved facial contours and enhanced facial symmetry following the procedure.

STYLAGE® XL BI-SOFT® Drug Interactions

It is important to consider potential drug interactions before administering STYLAGE® XL BI-SOFT®.

• Medications affecting liver metabolism: Caution is advised when using STYLAGE® XL Lidocaine in combination with drugs that inhibit liver metabolism, as this may affect the breakdown of lidocaine.
• Anticoagulants and blood thinners: Increased risk of bruising and hematoma formation in patients taking anticoagulants like aspirin or vitamin C. These medications should be discontinued prior to the procedure, with consultation from a healthcare provider.

STYLAGE® XL BI-SOFT® Advice for Patients

Patients should be well informed about the aftercare necessary following treatment with STYLAGE® XL BI-SOFT®. Key instructions include:

• Sun protection: Apply sunscreen with high SPF for at least two weeks after the treatment.
• Makeup: Avoid wearing makeup for 12 hours post-injection to reduce the risk of irritation or infection.
• Avoid heat exposure: Refrain from exposing the treated area to extreme heat (e.g., saunas or UV light) and cold until the swelling subsides.
• Massage: Patients should not massage or apply pressure to the treated area for 3 days post-treatment to allow the product to settle properly.