Polynucleotide aesthetics represents a promising development that provides a treatment to improve skin quality and enhance hydration and aesthetic outcomes. The therapeutic properties of DNA-derived polynucleotides make them essential for aesthetic practitioners to use in their practice.
Let’s see what modern research says about polynucleotide therapy together with their performance, outcomes, and position within aesthetic medicine.
Key Takeaways
- The skin benefits from polynucleotide treatment because it enhances collagen production, which results in improved skin texture and elasticity.
- These regenerative substances function as an alternative to standard dermal fillers.
- Polynucleotides are widely used in medical aesthetics for facial rejuvenation through injections, as well as for treating dark circles and fine lines with targeted under-eye applications.
- These treatments show excellent compatibility with polynucleotides and Botox injections, which leads to better combined outcomes.
- The application of polynucleotide skin boosters enhances both skin water content and cell healing processes.
- Patients who want natural, long-term skin improvements should consider polynucleotides as their treatment option.
- The anti-inflammatory properties of polynucleotides help minimize redness and irritation that occur after treatment.
Understanding Polynucleotides in Aesthetic Medicine
Natural polynucleotides play a crucial role in cellular repair and tissue regeneration within the body. Their biocompatibility makes them ideal for use in aesthetic medicine, where they are incorporated into advanced skincare treatments.
Polynucleotide-based facial treatments offer a revolutionary solution for restoring skin vitality and promoting long-term rejuvenation.
Mechanism of Action
- The cellular activity of fibroblasts receives an enhancement from polynucleotides, which subsequently leads to collagen and elastin synthesis.
- Enhanced microcirculation improves oxygen delivery to the skin, promoting better nourishment and overall skin health.
- The anti-inflammatory characteristics of polynucleotides minimize skin redness and post-treatment inflammation.
- Polynucleotides enhance skin quality gradually by activating tissue remodeling and regeneration.
Applications of Polynucleotides in Aesthetics
Naturally occurring skin polynucleotides function as essential molecules that support cellular repair and promote tissue regeneration.
Polynucleotides’ biocompatibility makes them ideal components for aesthetic medicine products designed to enhance skin regeneration and rejuvenation. These products work to restore skin vitality, making them a revolutionary solution for polynucleotide-based facial treatments.
Polynucleotides for Skin Rejuvenation
Skin texture improvement and hydration are the main benefits of using polynucleotides in mesotherapy and polynucleotide microneedling procedures.
The skin-restoring properties of polynucleotides establish them as an efficient medical solution for treating wrinkles, fine lines, and dull skin. The 2024 study highlights the role of polynucleotides as a key component in treatment for these problems, particularly in stimulating fibroblasts and keratinocytes to produce collagen and hyaluronic acid. Additionally, PN has demonstrated anti-inflammatory and antioxidant properties, further supporting its efficiency in skin repair and rejuvenation.
Polynucleotides function to repair skin damage that results from both UV rays and environmental aggressors.
Polynucleotides Under Eyes
The use of polynucleotides under the eyes has gained significant popularity in aesthetic medicine due to its ability to effectively target multiple concerns, including dark circles, puffiness, and fine lines. By enhancing microcirculation and collagen production, polynucleotides help reduce pigmentation, minimize swelling, and improve skin elasticity.
This non-invasive procedure is particularly beneficial for individuals with tired-looking eyes or age-related skin laxity, providing long-lasting, natural-looking rejuvenation.
Polynucleotides Injections vs. Traditional Fillers
The primary purpose of polynucleotide injections is to promote long-term skin regeneration instead of providing immediate volume restoration, which is a characteristic of hyaluronic acid fillers.
The treatment offers patients an outstanding option to achieve natural-looking enhancements. Unlike fillers that provide temporary volume, polynucleotides support the skin’s natural healing processes and enhance its firming capabilities, promoting long-term regeneration and rejuvenation. Compared to traditional fillers, polynucleotides offer longer-lasting results and a lower risk of complications.
Combination Treatments: Polynucleotides and Botox
The skin benefits from improved elasticity and hydration when polynucleotides work together with neuromodulators such as Botox. The joint application of these treatments extends both the duration and performance of anti-wrinkle therapies.
The combined use of these treatments creates an anti-aging strategy that combats muscle movement while performing skin regeneration.
Polynucleotides for Acne Scars and Hyperpigmentation
The effectiveness of polynucleotide skin boosters extends to acne scars and hyperpigmentation reduction through their ability to trigger cellular turnover and collagen production in the skin. These powerful regenerative molecules work by accelerating the skin’s natural healing process, encouraging the renewal of damaged cells, and improving overall skin texture
By repairing the dermal layers, polynucleotides help smooth out acne scars, reducing their depth and visibility over time. Additionally, they aid in balancing melanin production, leading to a more even skin tone and reducing the appearance of hyperpigmentation.
Top Polynucleotides Products and Brands
Aesthetic medicine practitioners have chosen several polynucleotide brands because of their proven success in medical applications. The most recognized polynucleotide products include Nucleofill and Croma.
- Croma PhilArt Eye – Specially formulated for the delicate under-eye area, this product reduces dark circles, puffiness, and fine lines while improving skin elasticity and hydration.
- Nucleofill Medium – A versatile polynucleotide injectable designed to enhance skin texture, stimulate collagen production, and provide deep hydration for long-term skin rejuvenation.
- Nucleofill Medium Plus – An advanced formulation offering enhanced bio-revitalization benefits, improving skin firmness and elasticity while reducing signs of aging.
- Nucleofill Soft Plus – Ideal for sensitive and delicate skin areas, this product deeply hydrates and supports skin regeneration, making it perfect for treating early signs of aging.
- Nucleofill Strong – A high-strength polynucleotide treatment designed to address advanced skin aging, deep wrinkles, and skin laxity, promoting long-lasting firming and rejuvenation.
These polynucleotide products provide safe and effective solutions for skin restoration, hydration, and anti-aging, making them essential in modern aesthetic medicine.
Potential Side Effects and Considerations
The application of polynucleotides on the skin is generally well-tolerated, making it a safe and effective option for skin rejuvenation. However, as with any aesthetic treatment, some individuals may experience mild, temporary side effects. These potential reactions include:
- Mild swelling or redness at the injection site, which typically subsides within a few hours to a couple of days.
- Temporary bruising, particularly in areas with delicate or thin skin, can be minimized with proper post-treatment care.
- Minimal discomfort following the procedure is usually described as slight tenderness or sensitivity that resolves quickly.
- Rare allergic reactions in hypersensitive individuals, though polynucleotides are biocompatible and well-accepted by the body.
Individuals who have autoimmune diseases or severe allergies need to seek medical advice before receiving polynucleotide treatment. The best healing results happen when patients stay out of direct sunlight and perform only light activities following their treatment.
Conclusion
Aesthetic medicine has advanced through the implementation of polynucleotide aesthetics as an essential non-surgical method to rejuvenate skin.
Aesthetic practitioners find polynucleotides to be very useful since these products enhance natural skin healing while hydrating tissue, and are also working well with other treatment methods. Polynucleotide brands serve as essential components for modern regenerative aesthetics while their application range continues to grow.
High-quality polynucleotide products specifically designed for medical practices can be found at Medical Spa RX.
Frequently Asked Questions
1. How long do the effects of polynucleotides last?
The duration of polynucleotide effects depends on skin health and treatment frequency and ranges from 6 months to 12 months. Multiple treatment sessions are needed by specific patients to achieve maximum long-term results.
2. Are polynucleotides safe for all skin types?
Polynucleotide products are safe for all skin types due to their high biocompatibility, making them suitable even for sensitive skin. Polynucleotides deliver their best benefits to skin that shows signs of aging and dehydration.
3. Can I combine polynucleotides with other treatments?
The use of polynucleotides proves compatible with other treatment methods. Patients often achieve better results by using polynucleotides together with Botox or through the combination of polynucleotide microneedling and chemical peels. Laser resurfacing procedures benefit from using polynucleotide skin boosters because they speed up recovery after treatment.
4. How soon can I see results?
The first treatment produces visible improvements that become noticeable between two and four weeks post-treatment, while additional enhancements develop progressively. Multiple treatment sessions lead to the best results.
5. Can polynucleotides be used for body treatments?
Polynucleotides function as body treatment products that dermatologists apply to the neck, décolle area, and hand areas to enhance skin hydration and quality.
References
- Lee KWA, Chan KWL, Lee A, Lee CH, Wan J, Wong S, Yi KH. Polynucleotides in Aesthetic Medicine: A Review of Current Practices and Perceived Effectiveness. Int J Mol Sci. 2024 Jul 27;25(15):8224. doi: 10.3390/ijms25158224. PMID: 39125793; PMCID: PMC11311621.
- William Richard Webb, Rahman E, Rao P, et al. Points to ponder on the role of polynucleotides in regenerative and aesthetic medicine: a systematic review. European Journal of Plastic Surgery. 2024;47(1). doi:https://doi.org/10.1007/s00238-024-02209-x
- Lee D, Choi H, Yoo K, et al. Assessment of current practices and perceived effectiveness of injectable polynucleotide for enlarged facial pores among cosmetic physicians: A survey‐based evaluation. Skin Research and Technology. 2024;30(9). doi:https://doi.org/10.1111/srt.13738
- Lampridou S, Bassett S, Cavallini M, Christopoulos G. The Effectiveness of Polynucleotides in Esthetic Medicine: A Systematic Review. Journal of Cosmetic Dermatology. Published online December 8, 2024. doi:https://doi.org/10.1111/jocd.16721
